hICOSL

Nomenclature

C57BL/6Smoc-Icosl^{em1(hICOSLG) Smoc}

Cat. NO.

NM-HU-00095

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
ICOSL

Synonyms

B7h; GI50; GL50; B7-H2; LICOS; B7RP-1; GL50-B; ICOS-L; Icoslg; Ly115l; AU044799; BG071784; mKIAA0653

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

ICOSLG

Model Description

The endogenous mouse Icosl gene was replaced by human ICOSL gene . While hICOSL(2)(Stock No.NM-HU-2000068) mice function similarly to hICOSL mice,for more detailed information please contact our technical advisor.

Research Application：Immunotherapy,cancer research,drug screening

*Literature published using this strain should indicate: hICOSL mice (Cat. NO. NM-HU-00095) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig1. Detection of hICOSL expression on human PBMC.

Fig2. Detection of hICOSL expression on activated APCs by LPS in hICOS/hICOSL dKI mice.

hICOS/hICOSL Strain Name：C57BL/6Smoc-Icosl^em1(hICOSLG)Icos^em1(hICOS)/Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-18018
Icosl-KO(3) Strain Name：C57BL/6Smoc-Icosl^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-210308
Icosl-Flox Strain Name：C57BL/6Smoc-Icosl^{em1(flox)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-CKO-200330
hICOSL(2) Strain Name：C57BL/6Smoc-Icosl^{tm3(hICOSLG)/Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-2000068
Icosl-KO Strain Name：C57BL/6Smoc-Icosl^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190721

U-GEMMs

Other Models

Models

hICOSL

Gene Summary

Model Description

Validation Data

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U-GEMMs

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Gene Summary

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