hOX40(2)

Nomenclature

C57BL/6Smoc-Tnfrsf4^{em3(hTNFRSF4) Smoc}

Cat. NO.

NM-HU-00078

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Tnfrsf4

Synonyms

Ox40; ACT35; CD134; Ly-70; Txgp1; TXGP1L

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

TNFRSF4

Model Description

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.

Research Application：cancer research,Immunotherapy,drug screening

*Literature published using this strain should indicate: hOX40(2) mice (Cat. NO. NM-HU-00078) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig1. Detection of hOX40 expression in splenocyte-derived activated T cells in hOX40 KI mice.

Note. Splenocytes from C57BL/6 and homozygous hOX40 mice were stimulated with ConA in vitro.

hPD-L1/hOX40 Strain Name：C57BL/6Smoc-Cd274^em1(hPD-L1)Tnfrsf4^{em1(hTNFRSF4)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-00111
hCD40/hOX40 Strain Name：C57BL/6Smoc-Cd40^em(hCD40)Tnfrsf4^{em(hTNFRSF4)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-220645
hIL13/hOX40 Strain Name：C57BL/6Smoc-Il13^em2(hIL13)Tnfrsf4^{em1(hTNFRSF4)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-220024
hPD-1/hOX40 Strain Name：C57BL/6Smoc-Pdcd1^em1(hPDCD1)Tnfrsf4^{em3(hTNFRSF4) Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-00108
hTLR9/hOX40 Strain Name：C57BL/6Smoc-Tlr9^tm1(hTLR9)Tnfrsf4^{em3(hTNFRSF4)/Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-190024

U-GEMMs

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Models

hOX40(2)

Gene Summary

Model Description

Validation Data

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U-GEMMs

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Models

hOX40(2)

Gene Summary

Model Description

Validation Data

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