hIL5/hIL5R(2)

Nomenclature

C57BL/6Smoc-Il5tm3(hIL5)Il5raem2(hIL5RA)Smoc

Cat. NO.

NM-HU-220010

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
IL5

Synonyms

Il-5

NCBI ID

16191

MGI ID

96557

Ensembl ID

ENSMUSG00000036117

Pubmed

IL5

Human Ortholog

IL5

Gene Symbol
IL5Ra

Synonyms

Il5r; CD125; CDw125

NCBI ID

16192

MGI ID

96558

Ensembl ID

ENSMUSG00000005364

Pubmed

IL5Ra

Human Ortholog

IL5RA

Model Description

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

image.png

Fig1. Expression of hIL5R on Bone marrow-derived eosinophils in hIL5/hIL5R(2) KI mice.

Note: Eosinophils were derived from bone marrow cells through culture with rmSCF, rmFLT-3L, and rmlL-5.

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