hSORT1

Nomenclature

C57BL/6Smoc-Sort1em1(hSORT1)Smoc

Cat. NO.

NM-HU-225035

Strain State

Repository Live

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Gene Summary

Gene Symbol
Sort1

Model Description

The endogenous mouse Sort1 gene was replaced by human SORT1 gene.

Validation Data

image.png

Fig1. Detection of SORT1 expression in lung and colon by RT-PCR. 

Wild type: only one band at 205 bp with primers F1/R1(mSort1);

Heterozygous: one band at 205 bp with primers F1/R1(mSort1) and one band at 193 bp with primers F2/R2 (hSORT1). 

Abbr.. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human SORT1 expression in lung in hSORT1 knockin mice by WB. 

Abbr. HO, homozygous; WT, wild type.

Note: The anti-human SORT1 antibody cross-reacted with mouse SORT1 and humanized SORT1.


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