hSERPINC1
Nomenclature
C57BL/6Smoc-Serpinc1tm1(hSERPINC1)Smoc
Cat. NO.
NM-HU-225075
Strain State
Repository Live
Gene Summary
Gene Symbol
Serpinc1
Model Description
The endogenous mouse Serpinc1 gene was replaced by human SERPINC1 gene.
Validation Data
Fig1. Detection of SERPINC1 expression in liver by RT-PCR.
Wild type: only one band at 250 bp with primers F1/R1 (mSerpinc1);
Homozygous: only one band at 374 bp with primers F2/R2 (hSERPINC1).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig2. Detection of hSERPINC1(A) and mSERPINC1(B) expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Fig3. Detecion of coagulation time in hSERPINC1 knockin mice by APTT(n=3).
Abbr. HO, homozygous; WT, wild type.
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