U-GEMMs

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6Smoc-Wsb1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Wsb2em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Wscd1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Wscd2em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-233844
Mice
Strain Name:C57BL/6Smoc-Wt1Osem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Wtipem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191058
Research Application:Cancer, acute myeloid leukemia, cervical cancer
Mice
Strain Name:C57BL/6Smoc-Wwc1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191059
Research Application:Nervous system, synaptic plasticity
Mice
Strain Name:C57BL/6Smoc-Wwc2em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Wwoxem2Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-231792
Mice
Strain Name:C57BL/6Smoc-Wwp1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190556
Research Application:E3 ubiquitin-ligase molecules and regulate a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing.
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