Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice	Akr1Cl-KO Strain Name：C57BL/6Smoc-Akr1Cl^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Akr1D1-KO Strain Name：C57BL/6Smoc-Akr1D1^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Akr7A5-KO Strain Name：C57BL/6Smoc-Akr7A5^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Akt1-KO Strain Name：C57BL/6Smoc-Akt1^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190741 Disease Connection：schizophrenia
Mice	Akt1s1-KO Strain Name：C57BL/6Smoc-Akt1S1^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-191102 Research Application：Ischemic brain injury; tumor
Mice	Akt2-KO Strain Name：C57BL/6Smoc-Akt2^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190742 Disease Connection：type 2 diabetes mellitus, polycystic ovary syndrome
Mice	Akt3-KO Strain Name：C57BL/6Smoc-Akt3^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-191091 Research Application：Cell proliferation,differentiation,apoptosis,tumorigenesis,glycogen synthesis and glucose uptake; nervous system,brain development,epilepsy
Mice	Aktip-KO Strain Name：C57BL/6Smoc-Aktip^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-200812
Mice	Alad-KO Strain Name：C57BL/6Smoc-Alad^em¹^Smoc Strain State：Developing \| Cat. NO.：NM-KO-241480
Mice	Alas1-KO Strain Name：C57BL/6Smoc-Alas1^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-210318

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U-GEMMs

Other Models

U-GEMMs

Knockouts