U-GEMMs

Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice
Strain Name:C57BL/6Smoc-Alox5em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-226149
Mice
Strain Name:C57BL/6Smoc-Alox5apem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-201388
Mice
Strain Name:C57BL/6Smoc-Alox8em1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-Alpiem1Smoc
Strain State:Developing | Cat. NO.:TBD
Mice
Strain Name:C57BL/6Smoc-AlpiemAkp3emSmoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220124
Mice
Strain Name:C57BL/6Smoc-Alpk1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-232783
Mice
Strain Name:C57BL/6Smoc-Alpk2em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-2101856
Mice
Strain Name:C57BL/6Smoc-Alpk3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-232920
Mice
Strain Name:C57BL/6Smoc-Alpltm1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-18058
Disease Connection:childhood hypophosphatasia, infantile hypophosphatasia
Mice
Strain Name:C57BL/6Smoc-Alppl2em1Smoc
Strain State:Developing | Cat. NO.:TBD
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