Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice	Appbp2-KO Strain Name：C57BL/6Smoc-Appbp2^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Appbp2Os-KO Strain Name：C57BL/6Smoc-Appbp2Os^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Appl1-KO Strain Name：C57BL/6Smoc-Appl1^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Appl2-KO Strain Name：C57BL/6Smoc-Appl2^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Aprt-KO Strain Name：C57BL/6Smoc-Aprt^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-201242 Disease Connection：adenine phosphoribosyltransferase deficiency
Mice	Aptx-KO Strain Name：C57BL/6Smoc-Aptx^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Aqp1-KO Strain Name：C57BL/6Smoc-Aqp1^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190915 Research Application：Aquaporin, eye movement imbalance, urine osmotic pressure
Mice	Aqp1-KO(2) Strain Name：C57BL/6Smoc-Aqp1^em²^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-233414
Mice	Aqp11-KO(2) Strain Name：C57BL/6Smoc-^Aqp11em²^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-232227
Mice	Aqp12-KO Strain Name：C57BL/6Smoc-Aqp12^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-201399

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U-GEMMs

Other Models

U-GEMMs

Knockouts