Adamts1-KO(2)

Nomenclature

C57BL/6Smoc-Adamts1em1Smoc

Cat. NO.

TBD

Strain State

Developing

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Gene Summary

Gene Symbol
Adamts1

Synonyms

C3-C5， METH1， ADAMTS， METH-1， ADAM-TS1， ADAMTS-1

NCBI ID

11504

MGI ID

109249

Ensembl ID

ENSMUSG00000022893

Pubmed

Adamts1

Human Ortholog

ADAMTS1

Model Description

Adamts1-KO(2) mice (Stock No.NM-KO-2115470）carry a knockout allele derived from the targeted deletion of exon 2. While Adamts1-KO mice (Stock No.NM-KO-200624) carrying the exon 5-7 deletion.

Disease Connection

urinary tract obstruction

Phenotype(s)

MGI:2450509

Reference(s)

Shindo T, Kurihara H, Kuno K, Yokoyama H, Wada T, Kurihara Y, Imai T, Wang Y, Ogata M, Nishimatsu H, Moriyama N, Oh-hashi Y, Morita H, Ishikawa T, Nagai R, Yazaki Y, Matsushima K, ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function [see comments]. J Clin Invest. 2000 May;105(10):1345-52

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