Aqp3-KO

Nomenclature

C57BL/6Smoc-Aqp3em1Smoc

Cat. NO.

NM-KO-200914

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Aqp3

Synonyms

AQP-2

NCBI ID

11828

MGI ID

1333777

Ensembl ID

ENSMUSG00000028435

Pubmed

Aqp3

Human Ortholog

AQP3

Model Description

Exon 2 of Aqp3 gene was deleted to generate Aqp3 knockout mice.

Disease Connection

Nephrogenic Diabetes Insipidus

Phenotype(s)

MGI:2174933

Reference(s)

Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS, Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4386-91

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