Trpm3-KO

Nomenclature

C57BL/6Smoc-Trpm3em1Smoc

Cat. NO.

NM-KO-235006

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Trpm3

Synonyms

MLSN2; LTRPC3; AU018608; 9330180E14; 6330504P12Rik; B930001P07Rik

NCBI ID

226025

MGI ID

2443101

Ensembl ID

ENSMUSG00000052387

Pubmed

Trpm3

Human Ortholog

TRPM3

Model Description

The exon 17 of Trpm3 gene was deleted to generate Trpm3 knockout mouse.

Disease Connection

Microphthalmia

Phenotype(s)

MGI:6727363

Reference(s)

Zhou Y, Bennett TM, Shiels A, Mutation of the TRPM3 cation channel underlies progressive cataract development and lens calcification associated with pro-fibrotic and immune cell responses. FASEB J. 2021 Feb;35(2):e21288

microphthalmia

Phenotype(s)

MGI:6727361

Reference(s)

Zhou Y, Bennett TM, Shiels A, Mutation of the TRPM3 cation channel underlies progressive cataract development and lens calcification associated with pro-fibrotic and immune cell responses. FASEB J. 2021 Feb;35(2):e21288

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