Cd274-KO(2)
Nomenclature
C57BL/6Smoc-Cd274em2Smoc
Cat. NO.
NM-KO-18044
Strain State
Repository Live
Gene Summary
Gene Symbol
Cd274
Model Description
Cd274 gene is also called B7-H1, Pdcd1lg1 or PD-L1. The PD-L1-KO(2) mouse model was obtained by deleting the Exon 3-5 region of mouse Cd274 gene. While PD-L1-KO(Stock No.NM-KO-00104) mice have been pulled from shelves for some reasons.
Validation Data
Fig1. Expression of PD-L1 in peritoneal macrophages, spleen cells and bone marrow cells from PD-L1 knockout mice is detected by FACS. The results showed that the expression of PD-L1 can not be detected in peritoneal macrophages, spleen cells and bone marrow cells of homozygous mice.
Reference(s)
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