Tnfrsf9-KO(2)

Nomenclature

C57BL/6Smoc-Tnfrsf9em1Smoc

Cat. NO.

NM-KO-210216

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Tnfrsf9

Synonyms

ILA， Ly63， 4-1BB， Cd137， CDw137， AA408498， AI325004， A930040I11Rik

NCBI ID

21942

MGI ID

1101059

Ensembl ID

ENSMUSG00000028965

Pubmed

Tnfrsf9

Human Ortholog

TNFRSF9

Model Description

Tnfrsf9(2) mice(Stock No.NM-KO-210216）carry a knockout allele derived from the targeted deletion of exon 2. While Tnfrsf9-KO mice (Stock No.NM-KO-190173) carrying the exon 3-5 deletion.

Disease Connection

Systemic Lupus Erythematosus

Phenotype(s)

MGI:3800222
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Fas-KO(BALB/c)(NM-KO-191206) mice.

Reference(s)

Ohta A, Sekimoto M, Sato M, Koda T, Nishimura S, Iwakura Y, Sekikawa K, Nishimura T, Indispensable role for TNF-alpha and IFN-gamma at the effector phase of liver injury mediated by Th1 cells specific to hepatitis B virus surface antigen. J Immunol. 2000 Jul 15;165(2):956-61

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