Cd36-KO

Nomenclature

C57BL/6Smoc-Cd36em1Smoc

Cat. NO.

NM-KO-190771

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cd36

Synonyms

FAT; GPIV; Scarb3

NCBI ID

12491

MGI ID

107899

Ensembl ID

ENSMUSG00000002944

Pubmed

Cd36

Human Ortholog

CD36

Model Description

Exon 5-9 of Cd36 gene was deleted to generate Cd36 knockout mice.
Research Application： this protein may have important functions as a cell adhesion molecule,Mutations in this gene cause platelet glycoprotein deficiency.

Disease Connection

Platelet-Type Bleeding Disorder 10

Phenotype(s)

MGI:3587412

Reference(s)

Febbraio M, Abumrad NA, Hajjar DP, Sharma K, Cheng W, Pearce SF , Silverstein RL, A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J Biol Chem. 1999 Jul 2;274(27):19055-62

Publications

Thrombospondin 1 improves hepatic steatosis in diet-induced insulinresistant mice and is associated with hepatic fat content in humans
References：Elseiver Sciense

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