Cckbr-KO
Nomenclature
C57BL/6Smoc-Cckbrem1Smoc
Cat. NO.
NM-KO-190609
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Cckbr
Model Description
Exon 3 of Cckbr gene was deleted to generate Cckbr knockout mice.
Research Application：This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
*Literature published using this strain should indicate: Cckbr-KO mice (Cat. NO. NM-KO-190609) were purchased from Shanghai Model Organisms Center, Inc..
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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