Chat-Flox
Nomenclature
C57BL/6Smoc-Chatem1(flox)Smoc
Cat. NO.
NM-CKO-200153
Strain State
Sperm cryopreservation
Gene Summary
Gene Symbol
Chat
Model Description
These mice carry loxP sites flanking exon 4-5 of Chat gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Chat gene.
Research Application：Research on neurotransmitter release cycle and sympathetic nerve pathway (preganglionic and postganglionic connection)
*Literature published using this strain should indicate: Chat-Flox mice (Cat. NO. NM-CKO-200153) were purchased from Shanghai Model Organisms Center, Inc..
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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