Clcn5-KO

Nomenclature

C57BL/6Smoc-Clcn5em1Smoc

Cat. NO.

NM-KO-200926

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Clcn5

Synonyms

Clc5， ClC-5， Sfc13， Clc4-1， T25545， Clcn4-1， DXImx42e， 5430408K11Rik， D930009B12Rik

NCBI ID

12728

MGI ID

99486

Ensembl ID

ENSMUSG00000004317

Pubmed

Clcn5

Human Ortholog

CLCN5

Model Description

Exon 6 of Clcn5 gene was deleted to generate Clcn5 knockout mice.

Disease Connection

Dent Disease

Phenotype(s)

MGI:3046533

Reference(s)

Piwon N, Gunther W, Schwake M, Bosl MR, Jentsch TJ, ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature. 2000 Nov 16;408(6810):369-73

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more