Ush2a-KO

Nomenclature

C57BL/6Smoc-Ush2aem1Smoc

Cat. NO.

NM-KO-201096

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ush2a

Synonyms

Gm676， Gm983， Ushrn， Mush2a， A930011D15Rik， A930037M10Rik

NCBI ID

22283

MGI ID

1341292

Ensembl ID

ENSMUSG00000026609

Pubmed

Ush2a

Human Ortholog

USH2A

Model Description

Exon 4 of Ush2a gene was deleted to generate Ush2a knockout mice.

Disease Connection

Usher Syndrome Type 2A

Phenotype(s)

MGI:3702269

Reference(s)

Liu X, Bulgakov OV, Darrow KN, Pawlyk B, Adamian M, Liberman MC, Li T, Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4413-8

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