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Exosome-derived circCCAR1 promotes CD8+T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

Model Organisms：Mice Product & Service：NMG Research field：hepatocellular carcinoma；exosome

Published date：2023-03-18 | References：Molecular Cancer

Chemokine Receptors CCR6 and PD1 Blocking scFv E27 Enhances Anti-EGFR CAR-T Therapeutic Efficacy in a Preclinical Model of Human Non-Small Cell Lung Carcinoma

Model Organisms：Mice Product & Service：M-NSG Research field：Non-Small Cell Lung Carcinoma

Published date：2023-03-12 | References：International Journal of Molecular Sciences

TREM2+ macrophages suppress CD8+ T-cell infiltration after transarterial chemoembolisation in hepatocellular carcinoma

Model Organisms：Mice Product & Service：Trem2-KO Research field：hepatocellular carcinoma

Published date：2023-03-06 | References：JOURNAL OF HEPATOLOGY

Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury

Model Organisms：Mice Product & Service：Me1-Flox Research field：Hepatic Ischemia/Reperfusion Injury；ferroptosis

Published date：2023-02-25 | References：ADVANCED SCIENCE

Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress

Model Organisms：Mice Product & Service：KPC Research field：Pancreatic Cancer

Published date：2023-02-24 | References：Gastroenterology

Distinct reward processing by subregions of the nucleus accumbens

Model Organisms：Mice Product & Service：Cartpt-IRES-Cre Research field：NAc subnuclei

Published date：2023-02-06 | References：Cell Reports

METTL3 is essential for normal progesterone signaling during embryo implantation via m6A-mediated translation control of progesterone receptor

Model Organisms：Mice Product & Service：Mettl3-Flox;Pgr-Cre Research field：

Published date：2023-01-24 | References：PNAS

A Cre knockin mouse reveals specifc expression of Agouti gene in mesenchymal lineage cells in multiple organs and provides a unique tool for conditional gene targeting

Model Organisms：Mice Product & Service：a-IRES-Cre Research field：Cre mice

Published date：2023-01-13 | References：SpringerLink

RIP3 impedes Mycobacterium tuberculosis survival and promotes p62-mediated autophagy

Model Organisms：Mice Product & Service：Ripk3-KO Research field：

Published date：2023-01-12 | References：PubMed

Molecular identification of bulbospinal ON neurons by GPER, which drives pain and morphine tolerance

Model Organisms：Mice Product & Service：Gper1-2A-Cre Research field：neuron

Published date：2023-01-03 | References：JCI

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