Chronic kidney diseases are highly diverse, but among them, there is a type of chronic kidney disease that may start showing signs in childhood. However, early symptoms are often subtle, leading to neglect by parents or misdiagnosis by doctors, resulting in delayed treatment. Moreover, this disease is hereditary, posing a high risk of developing into […]
We look forward to connecting with you at the upcoming AACR Annual Meeting in Chicago from April 25–30! At GenoBioTX, we understand that robust, translationally relevant preclinical models are critical for confident decision-making in oncology drug development. We specialize in developing genetically modified and humanized mouse models that provide the insights necessary to effectively evaluate […]
Cre-lox system, characterized by simple manipulation and high-efficiency recombinase, has been employed as a powerful tool of gene-editing. Application of Cre-lox system can achieve time-specific knock-out and knock-in of target genes in specified cells, tissues, and organisms, thereby regulating genes of interest spatiotemporally, which has profound impact on research of genetic function and animal modeling. […]
We provide gene editing techniques such as CRISPR/Cas9, transgenic approaches, or gene knockout strategies.
Researchers can request specific modifications to evaluate phenotypic changes, drug responses, or genetic interactions, facilitating the advancement of biomedical research and therapeutic developments.
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