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    2025.02.25

    The Hidden Killer in Chronic Kidney Disease – Alport Syndrome

    Chronic kidney diseases are highly diverse, but among them, there is a type of chronic kidney disease that may start showing signs in childhood. However, early symptoms are often subtle, leading to neglect by parents or misdiagnosis by doctors, resulting in delayed treatment. Moreover, this disease is hereditary, posing a high risk of developing into […]

    2024.11.01

    Overcome the Hurdle to Generate High Affinity and Diversity Antibodies to Self- or High Homology Antigens

    Registration link:  https://us06web.zoom.us/webinar/register/WN_zp48kyBhSH2rHpm_adFNIw Date: Thursday, Aug 28th, 2024; 2:00 pm EDT or 11:00 am PDT Webinar Highlights: This webinar will explore various methods for generating monoclonal antibodies, emphasizing the challenges of producing high-affinity antibodies to self or highly homologous antigens. Traditional methods, like in vitro screening and hybridoma-derived antibodies post-immunization, are cost-effective but struggle with […]

    2024.11.01

    How to Verify Your Cre-lox Model

    Now that the genetically engineered mice that carry a Cre-conditional (“floxed”) allele in target gene are at your hand. And the mice are supposed to express Cre in target tissue. The validation of your Cre-lox model become very indispensable, so here we advise you of some essential steps. Genotype the mice When unexpected phenotypes are observed during your working with mice, the […]

    Custom Gene-Modified Rat & Mouse Model Service Procedures

    We provide gene editing techniques such as CRISPR/Cas9, transgenic approaches, or gene knockout strategies.

    Researchers can request specific modifications to evaluate phenotypic changes, drug responses, or genetic interactions, facilitating the advancement of biomedical research and therapeutic developments.

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