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Mouse

LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis

Model Organisms：Mice Product & Service： Larp7-KO Research field：heart failure

Published date：2021-05-18 | References：Circulation

Programmed death protein 1 is essential for maintaining the anti-inflammatory function of infiltrating regulatory T cells in a murine spinal cord injury model

Model Organisms：Mice Product & Service：Rag1-KO(Rag1-EGFP) Research field：Spinal cord injury

Published date：2021-05-15 | References：Journal of Neuroimmunology

The endoribonuclease N4BP1 prevents psoriasis by controlling both keratinocytes proliferation and neutrophil infiltration

Model Organisms：Mice Product & Service：N4BP1-KO Research field：keratinocytes proliferation and neutrophil infiltration

Published date：2021-05-14 | References：Cell Death & Disease

Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3

Model Organisms：Mice Product & Service：Snx3-floxed Research field：Cardiovascular

Published date：2021-05-04 | References：CELL DEATH DIFFER

The IRENA lncRNA converts Chemotherapy-polarized tumor-suppressing Macrophages to Tumor-promoting Phenotypes in Breast Cancer

Model Organisms：Mouse Product & Service：R26-(CAG-IRENA);Csf1r-(IRES-iCre） Research field：antitumor immunity

Published date：2021-04-12 | References：Nature Cancer

Perivenous stellate cells are the main source of myofibroblasts and cancer‐associated‐fibroblasts formed after chronic liver injuries

Model Organisms：Mouse Product & Service：Col1a1-e(Kozak-BFP-WPRE-pA) Research field：Liver tumor

Published date：2021-04-05 | References：Hepatology

Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis

Model Organisms：Mice Product & Service：Pten-Flox Research field：hematopoietic stem cells homeostasis

Published date：2021-03-23 | References：Journal of Experimental Medicine

Pre-existing beta cells but not progenitors contribute to new beta cells in the adult pancreas

Model Organisms：Mouse Product & Service：Ins2-(Kozak-Dre-WPRE-pA) Research field：Diabetes

Published date：2021-03-16 | References：Nat Metab

Chemokine Receptor CCR2b Enhanced Anti-tumor Function of Chimeric Antigen Receptor T Cells Targeting Mesothelin in a Non-small-cell Lung Carcinoma Model

Model Organisms：N/A Product & Service：M-NSG Research field：Lung Carcinoma

Published date：2021-03-11 | References：Front. Immunol

MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche

Model Organisms：Mouse Product & Service：Map3k2-CKO,Rspo1-tdTomato ,Col1a2-CreERT2 Research field：Intestinal

Published date：2021-03-04 | References：Nature

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