hFOLR1

Nomenclature

C57BL/6Smoc-Folr1tm(hFOLR1)Smoc

Cat. NO.

NM-HU-220418

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Folr1

Model Description

The endogenous mouse Folr1 gene was replaced by human FOLR1 gene.

Validation Data

image.png

Fig.1 Detection of FOLR1 expression in kidney by RT-PCR. 

Wild type: only one band at 138 bp with primers F1/R1 (mFolr1);

Homozygous: only one band at 133 bp with primers F2/R2 (hFOLR1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human FOLR1 expression in hFOLR1 knockin mice by WB. 

Note. The anti-human FOLR1 antibody cross-reacted with mouse FOLR1 and humanized FOLR1.

Abbr. M, marker; HO, homozygous; WT, wild type.


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