Scgb1a1-IRES-Cre

Nomenclature

C57BL/6Smoc-Scgb1a1em1(IRES-Cre)Smoc

Cat. NO.

NM-KI-210120

Strain State

Repository Live

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Gene Summary

Gene Symbol
Scgb1a1

Synonyms

UG， UGB， Utg， CC10， CC16， CCSP， PCB-BP

NCBI ID

22287

MGI ID

98919

Ensembl ID

ENSMUSG00000024653

Pubmed

Scgb1a1

Human Ortholog

SCGB1A1

Model Description

IRES-Cre expression cassette was knocked into the Scgb1a1 gene.
Research Application：These mice express cre recombinase from the Scgb1a1 locus (secretoglobin). This strain may useful for in the research of bronchiolar non-ciliated Clara cells.

Validation Data

Scgb1a1-IRES-Cre-1.png

Fig.1 Cre-mediated recombination in the lung of  Scgb1a1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the bronchial and alveolar cells of  Scgb1a1Cre/+; Rosa26tdTomato/+ mouse. 

Scgb1a1-IRES-Cre-2.png

Fig.2 Detection of tdTomato(red) in various tissues of Scgb1a1Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the some cells of lung and spleen. Tdtomato can not be detected in the brain, pituitary gland, thymus, heart, stomach, kidney, pancreas, liver,lung, intestine, muscle, brown fats, submandibular gland, testis and epididymis. (For more detailed information please contact our technical advisor.)

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