Slc17a7-IRES-Cre

Nomenclature

C57BL/6Smoc-Slc17a7em1(IRES2-iCre)Smoc

Cat. NO.

NM-KI-200086

Strain State

Repository Live

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Gene Summary

Gene Symbol
Slc17a7

Synonyms

Vglut1; AI851913; 2900052E22Rik

NCBI ID

72961

MGI ID

1920211

Ensembl ID

ENSMUSG00000070570

Pubmed

Slc17a7

Human Ortholog

SLC17A7

Model Description

A IRES2-iCre expression cassette was knocked into the Slc17a7 gene stop codon site.
Research Application：Cre recombinase tool; Slc17a7(Sodium dependent Inorganic Phosphate cotransporter) is also known as Vglut1(Glutamate transporter). When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Slc17a7. This strain may be useful for studying glutamatergic synaptic vesicle trafficking and vesicle-bound, sodium-dependent phosphate transportation.

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of Slc17a7Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) is widely expressed in the brain of Slc17a7Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of Slc17a7Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the brain, pituitary gland, eyes, heart, skin and colon. TdTomato can also be detected in individual cells of the lung, liver, stomach, submandibular gland, brown fat, muscle, spleen, thymus, small intestine, pancreas, kidney and epididymis. (For more detailed information please contact our technical advisor.)


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