Ptf1a-CreERT2
Nomenclature
C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Cat. NO.
NM-KI-200118
Strain State
Repository Live
Gene Summary
Gene Symbol
Ptf1a
Model Description
Validation Data
Fig.1 CreERT2-mediated recombination in the pancreas of Ptf1aCreERT2/+ ; Rosa26tdTomato/+ mouse.
TdTomato(red) expression can be detected in the pancreatic acinar cells of Ptf1aCreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment.
Fig.2 Detection of tdTomato (red) in various tissues of Ptf1aCreERT2/+; Rosa26tdTomato/+ mice after tamoxifen treatment.
CreERT2-mediated recombination in the pancreatic acinar cells can be induced by tamoxifen. Some leakiness were detected in the pancreas prior to tamoxifen exposure. Besides, tdtomato expression can be detected in a few cells of the brain, pituitary gland and stomach. Tdtomato exprssion can not be detected in thymus, heart, lung, liver, testis, kidney, intestine, brown fat, spleen, submandibular gland, and muscle. (For more detailed information please contact our technical advisor.)
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