Isl1-CreERT2

Nomenclature

C57BL/6Smoc-Isl1^{em1(CreERT2) Smoc}

Cat. NO.

NM-KI-00013

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Isl1

Synonyms

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

ISL1

Model Description

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

Research Application：Cre recombinase tool

*Literature published using this strain should indicate: Isl1-CreERT2 mice (Cat. NO. NM-KI-00013) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig. 1 CreERT2-mediated recombination in the heart of Isl1^CreERT2/+；R26^tdtomato/+ mouse embryo at E13.5. The Isl1⁺ cell lineage (tdTomato) mainly contributes to the right ventricle at E13.5 of Isl1^CreERT2/+；R26^tdtomato/+. Tamoxifen was induced at E8.0. (Documented in the following reference.)

Publications

Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases
References：Circulation

Isl1-KO Strain Name：C57BL/6Smoc-Isl1^em¹^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-232739
Isl1-Frox Strain Name：C57BL/6Smoc-Isl1^{em1(frox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-2100710
Isl1-Dre Strain Name：C57BL/6Smoc-Isl1^{em1(Dre-Wpre-polyA)Smoc} Strain State：Repository Live \| Cat. NO.：NM-KI-200177
Isl1-Cre Strain Name：C57BL/6Smoc-Isl1^{em1(iCre-WPRE-pA)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-KI-200126

U-GEMMs

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Models

Isl1-CreERT2

Gene Summary

Model Description

Validation Data

Publications

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U-GEMMs

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Models

Isl1-CreERT2

Gene Summary

Model Description

Validation Data

Publications

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