Strain Model Specification

hSTING

Strain Name C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Catalog Number NM-HU-190036
Genetic Background C57BL/6Smoc
Synonyms ERIS, MPYS, Mita, STING, STING-beta, 2610307O08Rik
NCBI ID 72512, , , , , ↗
MGI ID 1919762, , , , , ↗
Ensembl ID ENSMUSG00000024349, , , , , ↗
Strain State Embryo cryopreservation
Research Application Immunotherapy,cancer research,drug screening

Validation Data

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Fig1 The expression of human STING in CD4+ T lymphocytes of humanized STING mice was measured by FACS. In heterozygous humanized STING mice, active expression of human STING was detected in CD4+ T lymphocytes derived from blood, spleen, thymus and lymph node. 

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Fig2 The expression of human STING in CD8+ T lymphocytes of humanized STING mice was measured by FACS. In heterozygous humanized STING mice, active expression of human STING was detected in CD8+ T lymphocytes derived from blood, spleen, thymus and lymph node. 

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Fig3 The expression of human STING in the heart and lung cells was measured by FACS. In heterozygous humanized STING mice, active expression of human STING was detected in the heart and lung cells .