Strain Model Specification

Cd19-IRES-DTRGFP

Strain Name C57BL/6Smoc-Cd19em2(IRES-DTREGFP)Smoc
Catalog Number NM-KI-190042
Genetic Background C57BL/6Smoc
Gene Symbol Cd19
Synonyms
NCBI ID 12478 ↗
MGI ID 88319 ↗
Ensembl ID ENSMUSG00000030724 ↗
Strain State Embryo cryopreservation

Validation Data

Validation data of EGFP expression

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Fig1.  Validation EGFP expression in PBMC by FACS. (Cooperation with CrownBio)

Validation data of DTR function

Heterozygous Cd19-IRES-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. After the tumors grew to 100 mm3, the Cd19-IRES-DTRGFP mice were injected with Diphtheria toxin. 

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Fig2. The growth of MC38 tumors in Heterozygous Cd19-IRES-DTRGFP mice and C57BL/6 mice. (Cooperation with CrownBio)

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Fig3. The percent of CD19+ cell in peripheral blood of MC38 tumor-bearing Cd19-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS. (Cooperation with CrownBio)

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Fig4. The percent of CD19+ cell in peripheral blood of MC38 tumor-bearing Cd19-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS. (Cooperation with CrownBio)