Strain Model Specification

Eno2-2A-Cre

Strain Name C57BL/6Smoc-Eno2em1(2A-iCre)Smoc
Catalog Number NM-KI-200012
Genetic Background C57BL/6Smoc
Gene Symbol Eno2
Synonyms NSE, Eno-2, AI837106, D6Ertd375e
NCBI ID 13807 ↗
MGI ID 95394 ↗
Ensembl ID ENSMUSG00000004267 ↗
Strain State Repository Live
Research Application Eno2 is a highly specific marker for neuronal and peripheral neuroendocrine cells. This strain is useful in the study of human motor neuron diseases such as brain injury and spinal muscular atrophy.

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse. 

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Fig. 2 Cre-mediated recombination in the spinal cord of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse. 

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Fig. 3 Detection of tdTomato(red) in various tissues of Eno2Cre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the brain and spinal cord. TdTomato can also be detected in individual cells of the pitultary gland, testis, heart, lung, liver, stomach, submandibular gland, brown fat, kidney, pancreas, intestine, colon, spleen, thymus, muscle and skin. (For more detailed information please contact our technical advisor.)