Strain Model Specification

Bhlha15-CreERT2

Strain Name C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Catalog Number NM-KI-200080
Genetic Background C57BL/6Smoc
Gene Symbol Bhlha15
Synonyms Mist1, Bhlhb8, MIST-1, 1810009C13Rik
NCBI ID 17341 ↗
MGI ID 891976 ↗
Ensembl ID ENSMUSG00000052271 ↗
Strain State Sperm cryopreservation
Research Application Cre recombinase tool, pancreatic acinar cells

Validation Data

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Fig. 1 CreERT2-mediated recombination in the intestine of Bhlha15CreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the crypt of Bhlha15CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. 

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Fig. 2 CreERT2-mediated recombination in the pancreas of Bhlha15CreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the pancreas of Bhlha15CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. Some leakiness can be detected in the pancreas prior to tamoxifen treatment.

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Fig. 3 Detection of tdTomato(red) in various tissues of Bhlha15CreERT2/+; Rosa26tdTomato/+ mice. Tdtomato is expressed in the pancreas, pituitary, stomach, crypt, salivary gland, lung, spleen, liver and kidney after tamoxifen treatment. Some leakiness can be detected in the salivary gland and pancreas prior to tamoxifen treatment. Tdtomato expression can not be observed in the brain, colon, heart, retina and skin. (For more detailed information please contact our technical advisor.)