Strain Model Specification

Myl1-NLS-Cre

Strain Name C57BL/6Smoc-Myl1em1(NLS-iCre-pA)Smoc
Catalog Number NM-KI-200124
Genetic Background C57BL/6Smoc
Gene Symbol Myl1
Synonyms Mylf, MLC1f, MLC3f, AI325107
NCBI ID 17901 ↗
MGI ID 97269 ↗
Ensembl ID ENSMUSG00000061816 ↗
Strain State Sperm cryopreservation
Research Application Cre-mediated recombination can be detected in the skeletal muscle of Myl1-Cre  mice. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre.

Validation Data

NM-KI-200124-Myl1-NLS-Cre-1.png

Fig. 1 Cre-mediated recombination in the skeletal muscle of Myl1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the skeletal muscle of Myl1Cre/+; Rosa26tdTomato/+ mouse. 

NM-KI-200124-Myl1-NLS-Cre-2.png

Fig. 2 Detection of tdTomato(red) in various tissues of Myl1Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the skeletal muscle. Tdtomato expression can also be detected in individual cells derived from liver, myocardium and brown fat. Tdtomato expression can not be observed in the brain and stomach. (For more detailed information please contact our technical advisor.)