Strain Model Specification

Scgb1a1-IRES-CreERT2

Strain Name C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc
Catalog Number NM-KI-200129
Genetic Background C57BL/6Smoc
Gene Symbol Scgb1a1
Synonyms UG, UGB, Utg, CC10, CC16, CCSP, PCB-BP
NCBI ID 22287 ↗
MGI ID 98919 ↗
Ensembl ID ENSMUSG00000024653 ↗
Strain State Sperm cryopreservation
Research Application These mice express creERT2 recombinase from the Scgb1a1 locus (secretoglobin). This strain may useful for in the research of bronchiolar non-ciliated Clara cells.

Validation Data

NM-KI-200129 Scgb1a1-IRES-CreERT2-1.png

Fig.1 CreERT2-mediated recombination in the lung of  Scgb1a1CreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the bronchial and alveolar cells of  Scgb1a1CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. 

NM-KI-200129 Scgb1a1-IRES-CreERT2-2.png

Fig. 2 Detection of tdTomato(red) in various tissues of Scgb1a1CreERT2/+; Rosa26tdTomato/+ mice. CreERT2 mediated recombination can be detected in the bronchial and alveolar cells after tamoxifen treatment. TdTomato expression can not be observed in the brain, pituitary gland, heart, liver, spleen, kidney, thymus, stomach, intestine, colon, submandibular gland, ovary, uterus, skin, muscle and brown fat. (For more detailed information please contact our technical advisor.)