hITGB1

Nomenclature

C57BL/6Smoc-Itgb1em1(hITGB1)Smoc

Cat. NO.

NM-HU-225040

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Itgb1

Model Description

The endogenous mouse Itgb1 gene was replaced by human ITGB1 gene.

Validation Data

image.png

Fig1. Detection of ITGB1 expression in bladder by RT-PCR. 

Wild type: only one band at 268 bp with primers F1/R1(mItgb1);

Homozygous: only one band at 363 bp with primers F2/R2(hITGB1); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of human ITGB1 expression in Kidney in C57BL/6 and HO hITGB1 mice by IHC. (Abbr. HO, homozygous; WT, wild type.)

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Fig3. Detection of human ITGB1 expression in Liver in C57BL/6 and HO hITGB1 mice by IHC. (Abbr. HO, homozygous; WT, wild type.)


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