U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Dll3em1(hDLL3) /Smoc
Strain State:Developing | Cat. NO.:NM-XA-240036
Mice
Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Epcamtm1(hEPCAM) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220123
Mice
Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Gpc3em1(hGPC3) /Smoc
Strain State:Repository Live | Cat. NO.:NM-XA-240037
Mice
Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd274em1(hPD-L1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220112
Mice
Strain Name:C57BL/6Smoc-Cd3etm(hCD3E)Cd3dtm(hCD3D)Cd3gtm(hCD3G)Folh1tm(hFOLH1B) /Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220251
Mice
Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tpbgem1(hTPBG) /Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220111
Mice
Strain Name:C57BL/6Smoc-Cd4em1(hCD4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00115
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd4tm(hCD4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230008
Mice
Strain Name:BALB/cAnSmoc-Cd4em3(hCD4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000053
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd40em1(hCD40) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00076
Research Application:cancer research,Immunotherapy,drug screening
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