U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Rag2emIl2rgemIl3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)Thpotm1(hTHPO)Sirpatm2(hSIRPA)Smoc
Strain State:Developing | Cat. NO.:NM-XA-234933
Mice
Strain Name:C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000019
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Il2rgem1Kdrtm2(hKDR)Rag2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220087
Mice
Strain Name:C57BL/6Smoc-Igs7em1(2xIns-DMPK 5‘region-pTRE-hDMPK(exon 11-15)-3'UTR(CTG)200-DMPK 1st intron-pA-2xIns)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-232261
Mice
Strain Name:C57BL/6Smoc-Igs7em1(tetO-EGFR-del19-IRES-GFP-2A-Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200258
Mice
Strain Name:C57BL/6Smoc-Igs7em1(tetO-EGFR(T790M)-del19-IRES-GFP-2A-Cre)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200259
Mice
Strain Name:C57BL/6Smoc-Igs7em(tetO-VEGFA165-IRES-EGFP-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-205000
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