U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Ighg1tm1(hIGHG1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225091
Mice
Strain Name:C57BL/6Smoc-Ighg1tm1(hIGHG4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225092
Mice
Strain Name:C57BL/6Smoc-Igsf8tm1(hIGSF8)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-231793
Mice
Strain Name:C57BL/6Smoc-Tg(hIL-8)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-225012
Mice
Strain Name:C57BL/6Smoc-Il10tm4(hIL10)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000063
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Il10ratm1(hIL10RA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215072
Mice
Strain Name:C57BL/6Smoc-Il10rbtm1(hIL10RB)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-234538
Mice
Strain Name:C57BL/6Smoc-Il11em1(hIL11)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204981
Mice
Strain Name:C57BL/6Smoc-Il11em1(hIL11)Il11ra1tm1(hIL11RA)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210372
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204982
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