U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Klrg1tm1(hKLRG1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234277
Mice
Strain Name:C57BL/6Smoc-Klrk1em1(hKLRK1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190005
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-L1camtm(hL1CAM)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220414
Mice
Strain Name:C57BL/6Smoc-H2-Aatm1(HLA-DPA1*02:02)H2-Ab1tm1(HLA-DPB1*03:01)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234679
Mice
Strain Name:C57BL/6Smoc-H2-Ab1em1(Kozak-HLA-DPB1*03:01-2A-HLA-DPA1*02:02-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234680
Mice
Strain Name:B6.129S-Lag3tm1(hLAG3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00049
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Lag3em1(hLAG3)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000051
Research Application:Immunotherapy,drug screening
Mice
Strain Name:B6.129S-Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190018
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Lair1em2(LAIR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000011
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Lair1em2(LAIR1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220040
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