U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Madcam1tm(hMADCAM1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220508
Mice
Strain Name:C57BL/6Smoc-Mapttm1(hMAPT)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200116
Mice
Strain Name:C57BL/6Smoc-Maptem2(hMAPT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200257
Research Application:Alzheimer's research
Mice
Strain Name:C57BL/6Smoc-Maptem1hMAPT-P301SSmoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-233262
Mice
Strain Name:C57BL/6Smoc-Marcoem1(hMARCO)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000029
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Masp1tm1(hMASP1/hMASP3)Smoc
Strain State:Developing | Cat. NO.:NM-HU-240082
Mice
Strain Name:C57BL/6Smoc-Masp2em1(hMASP2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000076
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Masp1tm1(h)Smoc
Strain State:Developing | Cat. NO.:NM-HU-231491
Mice
Strain Name:C57BL/6Smoc-Mc4rem1(hMC4R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233876
Mice
Strain Name:C57BL/6Smoc-Mc4rem1(hMC4R-R165W)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233884
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