hHLA-A2.1

Nomenclature

C57BL/6Smoc-H2-D1^{em1hHLA-A2*01}^Smoc

Cat. NO.

NM-KI-233927

Strain State

Repository Live

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Gene Summary

Gene Symbol
H2-D1

Synonyms

H-2D; H2-D; H2-K1

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

HLA-A，HLA-B，HLA-C

Gene Symbol
H2-D1

Synonyms

H-2D H2-D H2-K1

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

H2-D1

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Model Description

The endogenous mouse H2-D1 gene was replaced by human HLA-A2*01 gene .

*Literature published using this strain should indicate: hHLA-A2.1 mice (Cat. NO. NM-KI-233927) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig.1 Detection of mH-2D and HLA-A2 expression on overall Leukocytes in hHLA-A2.01 dKI mice (female, 6-8wks).

Fig.2 Analysis of leukocytes cell subpopulation in HO hHLA-A2.01 and WT C57BL/6 mice (female, 6-8wks, n=3).

Fig.3 Analysis of leukocytes cell subpopulation in Spleen (female, 6-8wks).

Fig.4 Analysis of leukocytes cell subpopulation in Blood (female, 6-8wks).

hHLA-A24.2/B2M Strain Name：C57BL/6Smoc-H2-D1^{em1(hB2M-linker-HLA-A24.2)}^Smoc Strain State：Developing \| Cat. NO.：NM-HU-241051
H2/H2-K1/H2-D1-KO(NMG) Strain Name：NOD.Cg-Prkdc^scidIl2rg^em1H2^emH2-K1^emH2-D1^emSmoc Strain State：Developing \| Cat. NO.：NM-KO-240516
hHLA-A2.1/B2M Strain Name：C57BL/6Smoc-H2-D1^{em1(hB2M/HLA-A2.1)}^Smoc Strain State：Developing \| Cat. NO.：NM-HU-234398
hB2M-HLA A2.1(NMG) Strain Name：NOD-Prkdc^scidIl2rg^em1H2-D1^{em1(hB2M-HLA A2.1)Smoc} Strain State：Developing \| Cat. NO.：NM-HU-225089
H2-D1-Flox Strain Name：C57BL/6Smoc-H2-D1^{em1(flox)Smoc} Strain State：Developing \| Cat. NO.：TBD

U-GEMMs

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Models

hHLA-A2.1

Gene Summary

Model Description

Validation Data

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U-GEMMs

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hHLA-A2.1

Gene Summary

Model Description

Validation Data

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