hHLA-A11

Nomenclature

C57BL/6Smoc-H2-K1^{tm1(hHLA-A11)Smoc}

Cat. NO.

NM-HU-204987

Strain State

Repository Live

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Gene Summary

Gene Symbol
H2-K1

Synonyms

K-f; H-2K; H2-K; H2-D1; H2-K_p; H-2K(d)

NCBI ID

MGI ID

Ensembl ID

Pubmed

Human Ortholog

HLA-A，HLA-E，HLA-F

Model Description

The endogenous mice H2-K1 gene was replaced by human HLA-A11 gene.

*Literature published using this strain should indicate: hHLA-A11 mice (Cat. NO. NM-HU-204987) were purchased from Shanghai Model Organisms Center, Inc..

Validation Data

Fig1. Detection of HLA-A11 expression in liver and spleen by RT-PCR.

Wild type: only one band at 369 bp with primers F1/R1(mH2-k1);

Heterozygous: one band at 369 bp with primers F1/R1(mH2-k1) and one band at 215 bp with primers F2/R2(hHLA-A11).

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

Fig2. Detection of HLA-A11 expression in blood in HLA-A11 KI mice.

hHLA-A11/hCD3EDG Strain Name：C57BL/6Smoc-H2-K1^{em1(hHLA-A11)}Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)^Smoc Strain State：Developing \| Cat. NO.：NM-XA-241039
hHLA-A11.1/B2M Strain Name：C57BL/6Smoc-H2-K1^{tm1(hB2M-linker-HLA-A1101)}^Smoc* Strain State：Developing \| Cat. NO.：NM-HU-241355
H2-K1-Flox Strain Name：C57BL/6Smoc-H2-K1^em^1(flox)^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-232188
H2/H2-K1-KO(NMG) Strain Name：NOD-Prkdc^scidIl2rg^em1h2^em2H2-K1^em2Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-NSG-006
H2-K1/H2-D1-KO Strain Name：C57BL/6Smoc-H2-K1^em1H2-D1^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-200606

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hHLA-A11

Gene Summary

Model Description

Validation Data

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