SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Cd22em2(hCD22)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000014
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Cd22em(hCD22)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220536
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Strain Name：C57BL/6Smoc-Cd226em(hCD226)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215012
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Strain Name：C57BL/6Smoc-Cd24aem1(hCD24-flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-231034
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Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210367
Research Application：inmmue therapy;drug screening
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Strain Name：C57BL/6Smoc-Cd248em1(hCD248)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225028
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Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190035
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2bem2(hFCGRT2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210405
Research Application：inmmue therapy; drug screening
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Strain Name：BALB/cAnSmoc-Cd27tm(hCD27)Pdcd1em(hPD-1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220339
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Strain Name：BALB/cAnSmoc-Cd27tm(hCD27)Cd274em(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220340
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