Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice	Ap4M1-KO Strain Name：C57BL/6Smoc-Ap4M1^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Ap4S1-KO Strain Name：C57BL/6Smoc-Ap4S1^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Ap5m1-KO Strain Name：C57BL/6Smoc-Ap5m1^em¹^Smoc Strain State：Developing \| Cat. NO.：NM-KO-242247
Mice	Ap5S1-KO Strain Name：C57BL/6Smoc-Ap5S1^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Ap5Z1-KO Strain Name：C57BL/6Smoc-Ap5Z1^em1Smoc Strain State：Developing \| Cat. NO.：TBD Disease Connection：hereditary spastic paraplegia 48
Mice	Apba1-KO Strain Name：C57BL/6Smoc-Apba1^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190747 Research Application：Synaptic Formation and Alzheimer's Disease related
Mice	Apba2-KO Strain Name：C57BL/6Smoc-Apba2^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Apba3-KO Strain Name：C57BL/6Smoc-Apba3^em1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-190748 Research Application：Alzheimer's Disease related
Mice	Apbb1-KO Strain Name：C57BL/6Smoc-Apbb1^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190749 Research Application：Beta-amyloid metabolism related;Alzheimer's disease research related
Mice	Apbb1ip-KO Strain Name：C57BL/6Smoc-Apbb1ip^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-200032 Research Application：Therapeutic antibody target

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U-GEMMs

Other Models

U-GEMMs

Knockouts