Knockouts

Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.

Mice	Apbb2-KO Strain Name：C57BL/6Smoc-Apbb2^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190750 Research Application：Beta-amyloid metabolism related;Alzheimer's disease research related;Synaptic Formation related.
Mice	Apc-KO Strain Name：C57BL/6Smoc-Apc^em2Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-200612 Disease Connection：colorectal cancer, familial adenomatous polyposis
Mice	Apc2-KO Strain Name：C57BL/6Smoc-Apc2^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Apcs-KO Strain Name：C57BL/6Smoc-Apcs^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-190001 Research Application：Immune-related
Mice	Apeh-KO Strain Name：C57BL/6Smoc-Apeh^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Apela-KO Strain Name：C57BL/6Smoc-Apela^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-210268 Disease Connection：pre-eclampsia
Mice	Apela-KO(2) Strain Name：C57BL/6Smoc-Apela^em2Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-210328 Disease Connection：pre-eclampsia
Mice	Apex2-KO Strain Name：C57BL/6Smoc-Apex2^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-201397
Mice	Aph1B-KO Strain Name：C57BL/6Smoc-Aph1B^em1Smoc Strain State：Developing \| Cat. NO.：TBD
Mice	Aph1C-KO Strain Name：C57BL/6Smoc-Aph1C^em1Smoc Strain State：Developing \| Cat. NO.：TBD

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U-GEMMs

Other Models

U-GEMMs

Knockouts