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Rare Disease

Rare diseases are those that affect only a small percentage of the world’s population. Most rare diseases are genetic. We provide many gene-engineered mouse models which are helpful for new therapies exploration and orphan drug development.

Mice	Gjb2-Flox Strain Name：C57BL/6Smoc-Gjb2^{em1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-210062 Disease Connection：autosomal recessive nonsyndromic deafness 1A, autosomal dominant keratitis-ichthyosis-deafness syndrome
Mice	Gjb2-KO Strain Name：C57BL/6Smoc-Gjb2^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-225057
Mice	Gla-KO Strain Name：C57BL/6Smoc-Gla^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-200601 Disease Connection：Fabry disease
Mice	Gnas-Flox Strain Name：C57BL/6Smoc-Gnas^{tm1(flox)Smoc} Strain State：Sperm cryopreservation \| Cat. NO.：NM-CKO-200300 Disease Connection：pseudohypoparathyroidism
Mice	Gns-KO Strain Name：C57BL/6Smoc-Gns^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-201161 Disease Connection：mucopolysaccharidosis III
Mice	Gpr143-KO Strain Name：C57BL/6Smoc-Gpr143^em1Smoc Strain State：Embryo cryopreservation \| Cat. NO.：NM-KO-200980 Disease Connection：ocular albinism
Mice	Grhpr-KO Strain Name：C57BL/6Smoc-Grhpr^em1Smoc Strain State：Repository Live \| Cat. NO.：NM-KO-210151 Disease Connection：primary hyperoxaluria type 2
Mice	Hbb-bs/Hbb-bt-KO Strain Name：C57BL/6Smoc-Hbb-bs^emHbb-bt^em¹^Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-KO-234923 Disease Connection：Beta thalassemia
Mice	hCD40L Strain Name：C57BL/6Smoc-Cd40lg^{tm1(hCD40L)/Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-2000033 Research Application：Immunotherapy,drug screening
Mice	hHBB Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bs^{tm1(hHBB)/Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-2000080 Research Application：Thalassemia research；drug screening

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