Nervous System
Principle The sciatic nerve of mice is partially ligated to simulate low back pain observed in human.
Sample requirements Male C57 mice of 8 weeks old
Testing instrument Dynamic Plantar Aesthesiometer (Von Frey, Ugo Basile)
Service cycle 14 business days
Figure 1 Modeling method
Principle The drug MPTP can disrupt the dopamine pathway between the mouse striatum and the substantia nigra to mimic human Parkinson's disease.
Sample requirements Male C57 mice of 10 weeks old
Testing instruments and consumables Rotating-beam fatigue-testing machine, climbing poles, MPTP (SIGMA)
Service cycle 14 business days
图1 MPTP Latency on Rotarod (sec)
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SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn moreAfter the base is put into operation, SMOC’s capability to provide genetically modified rat/mouse models and technical services including gene function research and drug development will be greatly enhanced.
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