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U-GEMMs

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Mice

Vip-IRES-Cre

Strain Name:C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200100

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.

Mice

Des-KO

Strain Name:C57BL/6Smoc-Desem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190261

This Des knockout mouse model was generated by knocking out the exon 2-5 region of the Des.

Mice

hPD-1/hPD-L1/hCTLA-4

Strain Name:C57BL/6Smoc-Pdcd1em1(hPD-1)Cd274em1(hPD-L1)Ctla4em1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200266

hCTLA4(NM-HU-00014),hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062)were crossed together to generate hPD-1/hPD-L1/hCTLA4 mice

Mice

Gpr65-IRES-Cre

Strain Name:C57BL/6Smoc-Gpr65em1(IRES-iCre)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200135

A IRES-iCre expression cassette was knocked into the Gpr65 gene stop codon site.

Mice

1700007K13Rik-KO

Strain Name:C57BL/6Smoc-1700007K13Rikem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-202002

Exon 2 of 1700007K13Rik gene was deleted to generate 1700007K13Rik knockout mice.

Mice

Eno2-2A-Cre

Strain Name:C57BL/6Smoc-Eno2em1(2A-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200012

A 2A-iCre expression cassette was knocked into the Eno2 gene stop codon site.

Mice

Nmu-2A-Cre

Strain Name:C57BL/6Smoc-Nmuem1(2A-Cre-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200298

2A-Cre-WPRE-polyA expression cassette was knocked into the Nmu gene stop codon site. Nmu gene encodes a member of the neuromedin family of neuropeptides. The encoded protein plays a role in energy homeostasis and body temperature regulation. And the protein is homologous with human NMU, which is linked toobesity.

Mice

Aadacl2fm1-Flox

Strain Name:C57BL/6Smoc-Aadacl2fm1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Aadacl2fm1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl2fm1 gene.

Mice

hCD3EDG/hTPBG

Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tpbgem1(hTPBG) /Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220111

hCD3EDG(NM-HU-220120) mice were crossed with hTPBG(NM-HU-200239) mice to generate hCD3EDG/hTPBG mice

Mice

AA986860-Flox

Strain Name:C57BL/6Smoc-AA986860em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of AA986860 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of AA986860 gene.

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