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U-GEMMs

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Mice

h4-1BB(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190077

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9(4-1BB) gene. While h4-1BB mice(Stock No.NM-HU-00099）have been pulled from shelves for some reasons.

Mice

hALB/hFCRN

Strain Name：C57BL/6Smoc-Albem3(hALB)Fcgrtem2(hFCGRT)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200278

hALB(NM-HU-200003)was crossed with hFcRn(NM-HU-190070)to generate hALB/hFCRN mice

Mice

hCD28

Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190011

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

hC5AR1/C5AR2

Strain Name：C57BL/6Smoc-C5ar1tm1(hC5AR1)C5ar2tm1(hC5AR2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000018

The endogenous mouse C5ar1 and C5ar2 gene was replaced by human C5AR1 and hC5AR2 gene.

Mice

hANGPT2

Strain Name：C57BL/6Smoc-Angpt2tm1(hANGPT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200247

The endogenous mice Angpt2 gene was replaced by human ANGPT2 gene.

Mice

hCD81

Strain Name：C57BL/6Smoc-Cd81em1(CD81)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190041

The endogenous mouse Cd81 gene was replaced by human CD81 gene.

Mice

h4-1BB(2)/hPD-1

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(h4-1BB)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200279

h4-1BB(2)(NM-HU-190077) was crossed with hPD-1(NM-HU-00015)to generate h4-1BB(2)/hPD-1 mice

Mice

hCD147

Strain Name：C57BL/6Smoc-Bsgtm1(hBSG)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000021

The endogenous mouse Bsg gene was replaced by human BSG gene.

Mice

hCD19

Strain Name：C57BL/6Smoc-Cd19em1(hCD19) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00110

The endogenous mouse Cd19 gene was replaced by human CD19 gene .

Mice

R26-CAG-LSL-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-luci-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18051

A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing.

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