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U-GEMMs

About 42,404 results
Mice

Mefv-hMEFV*V726A

Strain Name：C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

hBTLA(2)

Strain Name：C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190040

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014）have been pulled from shelves for some reasons.

Mice

hAPOC3

Strain Name：C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225050

The endogenous mouse Apoc3 gene was replaced by human APOC3 gene.

Mice

hC5

Strain Name：C57BL/6Smoc-Hcem1(hC5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000013

The endogenous mouse C5a gene was replaced by human C5 gene.

Mice

h4-1BB(2)/hCD3E(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210409

h4-1BB(2)(NM-HU-190077) was crossed with hCD3E(2)(NM-HU-210023)to generate h4-1BB(2)/hCD3E(2) mice.

Mice

Pten-KO

Strain Name：C57BL/6Smoc-Ptenem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

Mice

Ccr2-2A-DreERT2

Strain Name：C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200023

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

Mice

hCD3E

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

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