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U-GEMMs

About 42,406 results
Mice

hCCR8/hPD-1

Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Pdcd1em1(hPDCD1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210400

hCCR8(NM-HU-190053) was crossed with hPD-1(NM-HU-00015) to generate hCCR8/hPD-1 mice.

Mice

Itgam-IRES-hCD89/hIGHA1

Strain Name：C57BL/6Smoc-Itgamem1(IRES-hCD89-WPRE-polyA)sμtm1(hIGHA1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210412

Itgam-IRES-hCD89(NM-KI-200063) was crossed with hIGHA1(NM-HU-2000086) to generate Itgam-IRES-hCD89/hIGHA1 mice.

Mice

Clec4f-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Clec4fem1(IRES-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200070

A IRES-DTRGFP expression cassette was knocked into the Clec4f gene stop codon site.

Mice

A26c3-Flox

Strain Name：C57BL/6Smoc-A26c3em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A26c3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A26c3 gene.

Mice

Alb-2A-HSVTK(NMG)

Strain Name：NOD-Prkdcscid Il2rgem1Albem1(2A-HSVTK)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215046

2A-HSVTK expression cassette was knocked into the Alb gene.

Mice

hICOS/hICOSL

Strain Name：C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Itgax-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Itgaxem(T2A-tdTomato-P2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204992

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Itgax gene .

Mice

hSIGLEC10

Strain Name：C57BL/6Smoc-Siglecgtm1(hSIGLEC10)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000061

The endogenous mouse Siglecg gene was replaced by human SIGLEC10 gene.

Mice

hCCR8/hCTLA-4

Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210435

hCCR8(NM-HU-190053) was crossed with hCTLA4(NM-HU-00014) to generate hCCR8/hCTLA4 mice.

Mice

hOX40(2)

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00078

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.

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